منابع مشابه
High-throughput Cell Sorter with Piezoelectric Actuation.
Currently, most of the integrated sorting modules in the microfabricated DEP-based and fluorescent-activated cell sorters (μFACS) still suffer from low-throughput operation and require complex fabrication process (e.g. embedded electrodes) and high power consumption (e.g. electrokinetically-driven sorters). In this paper, we demonstrate an easy-to-fabricate, low-powered and high-speed sorting m...
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The integration of complete analyses systems "on chip" is one of the great potentials of microfabricated devices. In this study we present a new pressure-driven microfabricated fluorescent-activated cell sorter chip with advanced functional integration. Using this sorter, fluorescent latex beads are sorted from chicken red blood cells, achieving substantial enrichments at a sample throughput of...
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We present a high throughput (maximum flow rate approximately 10 microl/min or linear velocity approximately 3 mm/s) continuous bio-particle sorter based on 3D traveling-wave dielectrophoresis (twDEP) at an optimum AC frequency of 500 kHz. The high throughput sorting is achieved with a sustained twDEP particle force normal to the continuous through-flow, which is applied over the entire chip by...
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The movement of pro-apoptotic factors of the Bcl2-family from the cytosol to the mitochondria and the consequent permeabilization of the mitochondrial outer membrane to release cytochrome c and Smac from the mitochondrial intermembrane space into the cytosol or AIF to the nucleus are now well characterized steps in programmed cell death (Figure 1). However, there are concurrent movements of oth...
متن کاملHigh-throughput, motility-based sorter for microswimmers such as C. elegans.
Animal motility varies with genotype, disease, aging, and environmental conditions. In many studies, it is desirable to carry out high throughput motility-based sorting to isolate rare animals for, among other things, forward genetic screens to identify genetic pathways that regulate phenotypes of interest. Many commonly used screening processes are labor-intensive, lack sensitivity, and requir...
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ژورنال
عنوان ژورنال: Lab on a Chip
سال: 2015
ISSN: 1473-0197,1473-0189
DOI: 10.1039/c5lc00706b